Product Description :
TULAXINE Injectable Solution is a ready-to-use sterile parenteral preparation containing tulathromycin, a semi-synthetic macrolide antibiotic of the subclass triamilide.
TULAXINE consists of an equilibrated mixture of two isomeric forms of tulathromycin in a 9:1 ratio.

Indications:
Beef and Non-Lactating Dairy Cattle
BRD – TULAXINE Injectable Solution is indicated for the treatment of bovine respiratory disease (BRD) caused by Mannheimia haemolytica, Pasteurella multocida, Histophilus somni, and Mycoplasma bovis.
and for the control of respiratory disease in cattle at high risk of developing BRD caused by Mannheimia haemolytica, Pasteurella multocida, Histophilus somni,
and Mycoplasma bovis.
IBK – TULAXINE Injectable Solution is indicated for the treatment of infectious bovine keratoconjunctivitis (IBK) caused by Moraxella bovis.
Foot Rot – TULAXINE Injectable Solution is indicated for the treatment of bovine foot rot (interdigital necrobacillosis) caused by Fusobacterium necrophorum and Porphyromonas levii.
Suckling Calves, Dairy Calves, and Veal Calves
BRD – TULAXINE Injectable Solution is indicated for the treatment of BRD caused by M. haemolytica, P. multocida, H. somni, and M. bovis.
Swine
TULAXINE Injectable Solution is indicated for the treatment of swine respiratory disease (SRD) caused by Actinobacillus pleuropneumoniae, Pasteurella multocida, Bordetella bronchiseptica, Haemophilus parasuis, and Mycoplasma hyopneumoniae; and for the control of SRD caused by Actinobacillus pleuropneumoniae, Pasteurella multocida, and Mycoplasma hyopneumoniae in groups of pigs where SRD has been diagnosed.

DOSAGE:
Cattle: Inject subcutaneously as a single dose in the neck at a dosage of 2.5 mg/kg (1.1 mL/100 lb) body weight (BW) .
Do not inject more than 10 mL per injection site.
Swine: Inject intramuscularly as a single dose in the neck at a dosage of 2.5 mg/kg (0.25 mL/22lb) BW. Do not inject more than 2.5 mL per injection site.

Contraindications :
Do not use in case of hypersensitivity of the target animals to macrolide antibiotics.
Do not use simultaneously with other macrolides or lincosamides.
Do not use in lactating animals producing milk for human consumption.
Do not use in pregnant animals, which are intended to produce milk for human consumption, within 2 months of expected parturition.

Target species:
cattle, pigs and sheep

Withdrawal periods:
Cattle (meat and offal): 22 days.
Pigs (meat and offal): 13 days.
Sheep (meat and offal): 16 days.

Presentation:
50 ml multi-dose vial, packed in single box.

Storage conditions:
Keep out of the sight and reach of children.
Store at or below 77°F (25°C) with excursions between 59-86°F (15-30°C).

Description : Procam is a non-steroidal anti-inflammatory drug (NSAID) of the oxicam class.

Indications Cattle: For use in acute respiratory infection with appropriate antibiotic therapy to reduce clinical signs in cattle. For use in diarrhea in combination with oral re-hydration therapy to reduce clinical signs in calves of over one week of age and young, non-lactating cattle. For adjunctive therapy in the treatment of acute mastitis, in combination with antibiotic therapy. For the relief of post-operative pain following dehorning in calves. Sheep: For single dose use in sheep and lambs 14 days of age or older for the alleviation of pain and inflammation. Pigs: For use in non-infectious locomotor disorders to reduce the symptoms of lameness and inflammation. For adjunctive therapy in the treatment of puerperal septicemia and toxaemia (mastitis–metritis–agalactia syndrome) with appropriate antibiotic therapy. Horses: For use in the alleviation of inflammation and relief of pain in both acute and chronic Musculo-skeletal disorders. For the relief of pain associated with equine colic.

DOSAGE AND ADMINISTRATION: Cattle: Single subcutaneous or intravenous injection of 0.5 mg meloxicam / kg body weight (ie. 2.5 ml / 100 kg body weight) in combination with antibiotic therapy or oral rehydration therapy, as appropriate. Sheep: SINGLE USE ONLY by subcutaneous injection high on the neck behind the ear. For sheep and lambs from 14 days of age 1.0 mg meloxicam/kg bodyweight (i.e. 1.0 mL/20 kg bodyweight). Pigs: A single intramuscular injection of a dose of 0.4 mg meloxicam / kg body weight (ie 2.0 ml / 100 kg body weight) in combination with appropriate antibiotic therapy. If necessary, re-administration of meloxicam can be done after 24 hours. Horses: A single intravenous injection of 0.6 mg meloxicam / kg body weight (ie 3.0 ml / 100 kg body weight). Avoid contamination during use. The plug should not be punctured more than 20 times.

Contraindications : Do not use in horses less than 6 weeks of age. Do not use in animals suffering from impaired hepatic, cardiac or renal function and hemorrhagic disorders, or where there is evidence of ulcerogenic gastrointestinal lesions. Do not use in case of hypersensitivity to the active substance or to any of the excipients. For the treatment of diarrhea in cattle, do not use in animals of less than one week of age.

Target species: Cattle, sheep, horses and pigs.

Withdrawal periods : Cattle: Meat and offal: 15 days, Milk: 5 days. Sheep: meat or offal :11 days. Pigs: Meat and offal: 5 days. Horses: Meat and offal: 5 days.

Presentation: Colorless glass injection vials of 100 mL.

Storage: Keep out of the sight and reach of children. This veterinary medicinal product does not require any special storage conditions. Shelf life after first opening the container: 28 days.

Cattle, Sheep and Goat Treatment of Tryponosomiasis and Babeslosis

DOSAGE AND ADMINISTRATION:

Prepare the soIution by adding 15 ml of sterile water to each 2.36 g sachet Mix the prepared solution. Each sachet in sufficient for 300 kg of body weight.

WITHDRAWAL PERIOD:

Meat and offals: 21 days

Milk: 3 days.

STORAGE:

Store in a cool, dry, dark place below 30 °C.

Keep out of reach of children.

VETERINARY USE ONLY.

Indications:

For treatment of tick-transmitted theileriosis caused by the intracellular protozoan parasites Theileria parva (East Coast fever, Corridor disease, Zimbabwean theileriosis) and T. annulata (tropical theileriosis) in cattle. It is active against both the schizont and piroplasm stages of Theileria spp. and may be used during the incubation period of the disease, or when clinical signs are apparent.

Contra indications:

Due to the inhibiting effects of theileriosis on the immune system, vaccination should be delayed until the animal has recovered from theileriosis.

Side effects:

Localised, painless, oedematous swelling may occasionally be seen at the injection site.

Dosage:

For intramuscular injection.

The general dosage is 1 ml per 20 kg body weight.

PROPARVIQON is recommended to be given into the muscles of the neck. In severe cases the treatment may be repeated within 48 – 72 hours. Do not administer more than 10 ml per injection site. Successive injections should be administered at different sites.

Withdrawal times:

– For meat : 42 days.
– For milk : 2 days.

Target species:
Cattle, Sheep and goats

Packaging:

Vial 50 ml.

Clorsulon is a compound belonging to the benzene sulphonamide family which is recommended for the treatment and control of adult liver flukes (Fasciola hepatica and Fasciola gigantica) in cattle. Clorsulon inhibits the enzymes implicated in the glycolytic pathway, the primary source of energy in flukes. Further investigations indicated that clorsulon is a competitive inhibitor of  8-phosphoglycerate kinase and phospho-glyceromutase and blocks the oxidation of glucose to acetate and propionate. Clorsulon also depresses ATP levels in the fluke.

Nitroxynil is related monophenolic compound. The main pharmacological action of nitroxynil is fasciolicidal.  The lethal action against Fasciola hepatica has been demonstrated in vitro and in vivo in laboratory animals, and in sheep and cattle.  The mechanism of action is thought to be due to uncoupling of oxidative phosphorylation. Few other pharmacodynamic effects have been observed in therapeutic doses.

Indications:

Gastro-intestinal round worms:

Adult and immature: Ostertagia ostertagi – small brown stomach worms (including third and fourth stage larvae and inhibited immatures),

Haemonchus placei – barber’s pole worm

Trichostrongylus axie – stomach hair worm (including third and fourth stage larvae Trichostrongylus colubriformis – intestinal hair worm O.lyrata – stomach worm Cooperia spp – small intestinal worm (including third and fourth stage larvae) Oesophagostomum radiatum – nodule worm (including third and fourth stage larvae) Bunostoomum phlebotomum – (including third and fourth stage larvae) 

And adult stages of:

Trichuris spp – Whipworm

Strongyloides papillosus –intestinal worm-

Nematodirus spp – thin necked intestinal worm

Early immature (including 2-week old), Immature and Adult Liver Fluke Fasciola hepatica

Lungworms

Dictyocaulus viviparous (adult and immature, including inhibited stages).

Eyeworm Thelazia spp (adult stages)

Sucking Lice:

Linognathusvituli– Long nosed sucking louse

Haematopinuseurysternus– Short nosed sucking louse

Solenopotescapillatus– Little blue sucking louse.

Mites: Sarcoptes scabeivarbovis

Screw Worm Fly:

Chrysomya bezziana (parasitic larval stages Not reported in Australia but  present in Papua New Guinea).

Cattle tick:

Boophilus microplus

When used as directed for control of internal parasites of cattle, it concurrently aids in control of:

Mites:

Chorioptes bovis.

Biting Lice:

Bovicola (Damalinia) bovis

Dosage of Administration:

Route:   subcutaneous injection

For active ingredients:

200 µg ivermectin, 2 mg clorsulon per kg and nitroxynil 10.2 mg per kg live weight

For whole product:

5 mL per 50kg live weight

Special warning:

Sterilise all injection apparatus by boiling (or equivalent) before use. Avoid use of strong disinfectants on apparatus.

Maintain cleanliness at all times.

Keep needles sharp and clean. Replace frequently.

Use shortest needle possible, certainly not exceeding 15 mm.

As far as possible avoid injection of animals during wet weather or under dusty conditions.

This product should be injected only under the skin.

If possible inject high on the neck behind the ear. If required the dose can be divided and administered in two sites.

Special precautions:

Avoid overdosing of cattle.

Care should be taken when administering it or other medications to sick debilitated animals in poor condition. In these cases, a veterinarian should be contacted.

If product leaks from the injection site staining of the coat of light coloured cattle may occur for a period of several weeks. Inject in a downward motion to avoid loss of product and staining at the injection site. Exercise care where staining may be a disadvantage (eg. show cattle).

Gloves are recommended during usage

Contra – Indications:

Do not use in cattle which are producing or may in the future produce milk where the milk or milk products may be used for human consumption.

Adverse effects: None

Withdrawal time:

MEAT: do not use less than 56 days before slaughter for human consumption. Calves born to cows that have been treated with it during pregnancy must not be slaughtered for human consumption for 56 days after treatment of the dam.

MILK: do not use in cattle which are producing or may in the future produce milk where the milk or milk products may be used for human consumption.

Target species:

Cattle

Package:

50 ml, 100 ml ,250 mL, 500 ml and 1000 ml

USAGE AND DOSAGE

For subcutaneous injection

Cattle – pneumonia: 1 ml per 30 kg body weight (10 mg/kg).
Cattle – interdigital necrobacillosis: 0.5 ml per 30 kg body weight (5 mg/kg).
Sheep – pneumonia and mastitis: 1 ml per 30 kg body weight (10 mg/kg).
Sheep – footrot: 0.5 ml per 30 kg body weight (5 mg/kg).

CONTRA-INDICATIONS

Administration to equine, porcine or caprine species, or to lambs weighing 15 kg or less.
Administration to cattle producing milk for human consumption.
Do not use in heifers within 60 days of calving.
Do not use together with adrenalin or β-adrenergic antagonists such as propranolol.

WITHDRAWAL TIMES

For meat: Cattle: 60 days.

Sheep: 42 days.

For milk: Sheep: 15 days.

Presentation

Multidose vials of 250 mL.

Multidose vials of 100 mL.

Storage

Store in a cool, dry place, protected from light. store among 15º to 30ºC (59°-86°F).

Keep out of reach of children and domestic animals.

Reseal after each use.

Do not smoke or eat while handling the product.

Target Species

Cattle, camels, sheep, goats and dogs.

Applied parenterally, oxytetracycline penetrates quickly into the blood and tissues, but the advanced effect of this preparation is the extremely long therapeutic effect.

Oxytetracycline acts synergistic with polymyxin.

Indicated with infections caused by microorganisms susceptible to oxytetracycline, like infections of the respiratory tract (pneumonia, bronchopneumonia), infections of the urinary tract, enteritis, (endo)metritis, mastitis, foot rot and Bedsoniasis in sheep.

Contra‑Indications:

Hypersensitivity to tetracyclines, serious kidney and/or liver disturbances, combination with penicillins or cephalosporins.

Side-effects:

Hypersensitivity reactions, irritation at injection site.

Recommendations and Warnings:

Oxytetracycline is incompatible with preparations containing polyvalent cations (Ca ++, Mg++, Fe++), because of their known interference with tetracyclines.

Do not use between 5 days before till 5 days after vaccination.

Dosage and Administration:

The general dose is 20 mg/kg body weight, (= 1 ml solution per 10 kg body weight), deep intramuscular (3 days action). Avoid application of more than 10 ml per injection site. In severe cases the injection can be repeated after 3 days. Piglets till 10 kg maximal 1 ml subcutaneous.

Withdrawal time:

21 days before slaughtering and 7 days before milking.

Storage:

Store in a cool, dry place, protected from light. Store among 15º to 30ºC (59°-86°F).

Keep out of reach of children and domestic animals.

Reseal after each use.

Target Species:

Cattle, horses, swine and dogs.